Due to the anatomical positioning of the orbicularis oculi being very superficial it should easily act as shield to the deeper positioned muscles such as the zygomatic major and minor. Keeping you injection depth superficial also will safeguard and reduce the risk of effecting these muscles.

The most dangerous injection is an injection angled inferior and medially as shown above, that also becomes too deep. These injections may filter into the zygoma muscles rather than the intended orbicularis oculi. In addition to ensuring good technique, you can also reduce dosage to a more conservative and natural finish, opting for 2 units in this area as opposed to 4.